FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells

The chromatin regulator FACT (facilitates chromatin transcription) is essential for ensuring stable gene expression by promoting transcription. In a genetic screen using Caenorhabditis elegans, we identified that FACT maintains cell identities and acts as a barrier for transcription factor-mediated...

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Publicat a:Dev Cell
Autors principals: Kolundzic, Ena, Ofenbauer, Andreas, Bulut, Selman I., Uyar, Bora, Baytek, Gülkiz, Sommermeier, Anne, Seelk, Stefanie, He, Mei, Hirsekorn, Antje, Vucicevic, Dubravka, Akalin, Altuna, Diecke, Sebastian, Lacadie, Scott A., Tursun, Baris
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137076/
https://ncbi.nlm.nih.gov/pubmed/30078731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.07.006
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