Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3

Conjugation is fundamental for the acquisition of new genetic traits and the development of antibiotic resistance in pathogenic organisms. Here, we show that a hypothetical Clostridium perfringens protein, TcpK, which is encoded by the tetracycline resistance plasmid pCW3, is essential for efficient...

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Vydáno v:Nat Commun
Hlavní autoři: Traore, Daouda A. K., Wisniewski, Jessica A., Flanigan, Sarena F., Conroy, Paul J., Panjikar, Santosh, Mok, Yee-Foong, Lao, Carmen, Griffin, Michael D. W., Adams, Vicki, Rood, Julian I., Whisstock, James C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137059/
https://ncbi.nlm.nih.gov/pubmed/30213934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06096-2
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