Bayesian analysis of isothermal titration calorimetry for binding thermodynamics

Isothermal titration calorimetry (ITC) is the only technique able to determine both the enthalpy and entropy of noncovalent association in a single experiment. The standard data analysis method based on nonlinear regression, however, provides unrealistically small uncertainty estimates due to its ne...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Nguyen, Trung Hai, Rustenburg, Ariën S., Krimmer, Stefan G., Zhang, Hexi, Clark, John D., Novick, Paul A., Branson, Kim, Pande, Vijay S., Chodera, John D., Minh, David D. L.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136728/
https://ncbi.nlm.nih.gov/pubmed/30212471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203224
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