Coptisine-induced inhibition of Helicobacter pylori: elucidation of specific mechanisms by probing urease active site and its maturation process

In this study, we examined the anti-Helicobactor pylori effects of the main protoberberine-type alkaloids in Rhizoma Coptidis. Coptisine exerted varying antibacterial and bactericidal effects against three standard H. pylori strains and eleven clinical isolates, including four drug-resistant strains...

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Dettagli Bibliografici
Pubblicato in:J Enzyme Inhib Med Chem
Autori principali: Li, Cailan, Huang, Ping, Wong, Kambo, Xu, Yifei, Tan, Lihua, Chen, Hanbin, Lu, Qiang, Luo, Chaodan, Tam, Chunlai, Zhu, Lixiang, Su, Ziren, Xie, Jianhui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136390/
https://ncbi.nlm.nih.gov/pubmed/30191728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1501044
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