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A pyridoindole antioxidant SMe1EC2 regulates contractility, relaxation ability, cation channel activity, and protein-carbonyl modifications in the aorta of young and old rats with or without diabetes mellitus

We studied the effects of treatment with SMe1EC, a hexahydropyridoindole antioxidant, on vascular reactivity, endothelial function, and oxidonitrosative stress level of thoracic aorta in young and old rats with or without diabetes mellitus. The rats were grouped as young control (YC 3 months old), o...

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Dettagli Bibliografici
Pubblicato in:GeroScience
Autori principali: Şakul, Arzu, Arı, Nuray, Sotnikova, Ruzenna, Ozansoy, Gülgün, Karasu, Çimen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136298/
https://ncbi.nlm.nih.gov/pubmed/30054861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-018-0034-y
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