A novel high-throughput assay for respiration in isolated brain microvessels reveals impaired mitochondrial function in the aged mice

Cerebral blood flow (CBF) is uniquely regulated by the anatomical design of the cerebral vasculature as well as through neurovascular coupling. The process of directing the CBF to meet the energy demands of neuronal activity is referred to as neurovascular coupling. Microvasculature in the brain con...

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Detalhes bibliográficos
Publicado no:GeroScience
Main Authors: Sure, Venkata N., Sakamuri, Siva S. V. P., Sperling, Jared A., Evans, Wesley R., Merdzo, Ivan, Mostany, Ricardo, Murfee, Walter L., Busija, David W., Katakam, Prasad V. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136296/
https://ncbi.nlm.nih.gov/pubmed/30074132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-018-0037-8
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