Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood–brain barrier in Sprague–Dawley rats

BACKGROUND: Targeting endogenous blood–brain barrier (BBB) transporters such as organic anion transporting polypeptide 1a4 (Oatp1a4) can facilitate drug delivery for treatment of neurological diseases. Advancement of Oatp targeting for optimization of CNS drug delivery requires characterization of s...

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Bibliografiske detaljer
Udgivet i:Fluids Barriers CNS
Main Authors: Brzica, Hrvoje, Abdullahi, Wazir, Reilly, Bianca G., Ronaldson, Patrick T.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136214/
https://ncbi.nlm.nih.gov/pubmed/30208928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-018-0110-9
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