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The microRNA miR-21 Is a Mediator of FGF8 Action on Cortical COUP-TFI Translation
The morphogen FGF8 plays a pivotal role in neocortical area patterning through its inhibitory effect on COUP-TFI/Nr2f1 anterior expression, but its mechanism of action is poorly understood. We established an in vitro model of mouse embryonic stem cell corticogenesis in which COUP-TFI protein express...
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| Publicado no: | Stem Cell Reports |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6135738/ https://ncbi.nlm.nih.gov/pubmed/30174317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.08.002 |
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