AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells

In most cases, macroautophagy/autophagy serves to alleviate cellular stress and acts in a pro-survival manner. However, the effects of autophagy are highly contextual, and autophagic cell death (ACD) is emerging as an alternative paradigm of (stress- and drug-induced) cell demise. AT 101 ([-]-gossyp...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Meyer, Nina, Zielke, Svenja, Michaelis, Jonas B., Linder, Benedikt, Warnsmann, Verena, Rakel, Stefanie, Osiewacz, Heinz. D., Fulda, Simone, Mittelbronn, Michel, Münch, Christian, Behrends, Christian, Kögel, Donat
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Research Paper - Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135628/
https://ncbi.nlm.nih.gov/pubmed/29938581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1476812
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