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Combine and conquer: challenges for targeted therapy combinations in early phase trials
A better understanding of cancer biology has led to the development of targeted anticancer drugs. However, the full potential of these agents has not been realised due to the presence of de novo resistance, often resulting from compensatory signalling pathways or the development of acquired resistan...
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| Publicado no: | Nat Rev Clin Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6135233/ https://ncbi.nlm.nih.gov/pubmed/27377132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2016.96 |
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