Quercetin and doxorubicin co-delivery using mesoporous silica nanoparticles enhance the efficacy of gastric carcinoma chemotherapy

BACKGROUND: Effective gastric carcinoma (GC) chemotherapy is subject to many in vitro and in vivo barriers, such as tumor microenvironment and multidrug resistance. MATERIALS AND METHODS: Herein, we developed a hyaluronic acid (HA)-modified silica nanoparticle (HA-SiLN/QD) co-delivering quercetin an...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Fang, Jian, Zhang, Shangwu, Xue, Xiaofeng, Zhu, Xinguo, Song, Shiduo, Wang, Bin, Jiang, Linhua, Qin, Mingde, Liang, Hansi, Gao, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135215/
https://ncbi.nlm.nih.gov/pubmed/30233175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S170862
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