Design, Synthesis and Biological Activity Evaluation of S-Substituted 1H-5-Mercapto-1,2,4-Triazole Derivatives as Antiproliferative Agents in Colorectal Cancer

Colon cancer is a widespread pathology with complex biochemical etiology based on a significant number of intracellular signaling pathways that play important roles in carcinogenesis, tumor proliferation and metastasis. These pathways function due to the action of key enzymes that can be used as tar...

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Foilsithe in:Front Chem
Main Authors: Mioc, Marius, Avram, Sorin, Bercean, Vasile, Kurunczi, Ludovic, Ghiulai, Roxana M., Oprean, Camelia, Coricovac, Dorina E., Dehelean, Cristina, Mioc, Alexandra, Balan-Porcarasu, Mihaela, Tatu, Calin, Soica, Codruta
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2018
Ábhair:
Chemistry
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134806/
https://ncbi.nlm.nih.gov/pubmed/30234098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00373
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