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Downregulation of Matrix Metalloproteinases 2 and 9 is Involved in the Protective Effect of Trehalose on Spinal Cord Injury

Upregulation of matrix metalloproteinases (MMPs), in particular MMP-2 and MMP-9 contributes to secondary pathogenesis of spinal cord injury (SCI) via promoting inflammation. Recently, we have reported that trehalose suppresses inflammatory responses following SCI. Therefore, we investigated the effe...

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Détails bibliographiques
Publié dans:Int J Mol Cell Med
Auteurs principaux: Mirzaie, Masoumeh, Karimi, Mehrnaz, Fallah, Hossein, Khaksari, Mohammad, Nazari-Robati, Mahdieh
Format: Artigo
Langue:Inglês
Publié: Babol University of Medical Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134419/
https://ncbi.nlm.nih.gov/pubmed/30234068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22088/IJMCM.BUMS.7.1.8
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