GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation

There is no agnostic GWAS evidence for the genetic control of IL-1β expression in periodontal disease. Here we report a GWAS for “high” gingival crevicular fluid IL-1β expression among 4910 European-American adults and identify association signals in the IL37 locus. rs3811046 at this locus (p = 3.3 ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Offenbacher, Steven, Jiao, Yizu, Kim, Steven J., Marchesan, Julie, Moss, Kevin L., Jing, Li, Divaris, Kimon, Bencharit, Sompop, Agler, Cary S., Morelli, Thiago, Zhang, Shaoping, Sun, Lu, Seaman, William T., Cowley, Dale, Barros, Silvana P., Beck, James D., Munz, Matthias, Schaefer, Arne S., North, Kari E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134146/
https://ncbi.nlm.nih.gov/pubmed/30206230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05940-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados