Gastric cancer mesenchymal stem cells derived IL-8 induces PD-L1 expression in gastric cancer cells via STAT3/mTOR-c-Myc signal axis

The expression of PD-L1 in tumor cells is one of the main causes of tumor immune escape. However, the exact mechanism for regulating PD-L1 expression in gastric cancer (GC) cells remains unclear. Our previous studies have shown that mesenchymal stem cells (MSCs) exert broad immunosuppressive potenti...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Sun, Li, Wang, Qianqian, Chen, Bin, Zhao, Yuanyuan, Shen, Bo, Wang, Hua, Xu, Jing, Zhu, Miaolin, Zhao, Xiangdong, Xu, Changgen, Chen, Zhihong, Wang, Mei, Xu, Wenrong, Zhu, Wei
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134105/
https://ncbi.nlm.nih.gov/pubmed/30206229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0988-9
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