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Transcriptional Regulation Buffers Gene Dosage Effects on a Highly Expressed Operon in Salmonella

Highly expressed genes are commonly located close to the origin of replication of bacterial chromosomes (OriC). This location skew is thought to reflect selective advantages associated with gene dosage effects during the replication cycle. The expression of constitutively expressed genes can vary up...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Garmendia, Eva, Brandis, Gerrit, Hughes, Diarmaid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134099/
https://ncbi.nlm.nih.gov/pubmed/30206172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01446-18
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