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Angiopoietin-like protein 3 blocks nuclear import of FAK and contributes to sorafenib response

BACKGROUND: Poor drug response of sorafenib is a major challenge which reduces clinical benefit of renal cell carcinoma (RCC) patients. It is therefore of great clinical significance to elucidate the underlying mechanism to restore the therapeutic response to sorafenib. METHODS: Angiopoietin-like pr...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Bao, Yi, Yang, Fu, Liu, Bing, Zhao, Tangliang, Xu, Zhipeng, Xiong, Ying, Sun, Shuhan, Qu, Le, Wang, Linhui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134083/
https://ncbi.nlm.nih.gov/pubmed/30033448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0189-4
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