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Angiopoietin-like protein 3 blocks nuclear import of FAK and contributes to sorafenib response

BACKGROUND: Poor drug response of sorafenib is a major challenge which reduces clinical benefit of renal cell carcinoma (RCC) patients. It is therefore of great clinical significance to elucidate the underlying mechanism to restore the therapeutic response to sorafenib. METHODS: Angiopoietin-like pr...

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Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Bao, Yi, Yang, Fu, Liu, Bing, Zhao, Tangliang, Xu, Zhipeng, Xiong, Ying, Sun, Shuhan, Qu, Le, Wang, Linhui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134083/
https://ncbi.nlm.nih.gov/pubmed/30033448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0189-4
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