An Ad/MVA vectored Theileria parva antigen induces schizont-specific CD8(+) central memory T cells and confers partial protection against a lethal challenge

The parasite Theileria parva is the causative agent of East Coast fever (ECF), one of the most serious cattle diseases in sub-Saharan Africa, and directly impacts smallholder farmers’ livelihoods. There is an efficient live-parasite vaccine, but issues with transmission of vaccine strains, need of a...

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Pubblicato in:NPJ Vaccines
Autori principali: Svitek, Nicholas, Saya, Rosemary, Awino, Elias, Munyao, Stephen, Muriuki, Robert, Njoroge, Thomas, Pellé, Roger, Ndiwa, Nicholas, Poole, Jane, Gilbert, Sarah, Nene, Vishvanath, Steinaa, Lucilla
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134044/
https://ncbi.nlm.nih.gov/pubmed/30245859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-018-0073-5
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