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Pharmacokinetic principles in the inner ear: Influence of drug properties on intratympanic applications

Local drug delivery to the ear has gained wide clinical acceptance, with the choice of drug and application protocol in humans largely empirically-derived. Here, we review the pharmacokinetics underlying local therapy of the ear using the drugs commonly used in clinical practice as examples. Based o...

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Publicat a:Hear Res
Autors principals: Salt, Alec N., Plontke, Stefan K.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133771/
https://ncbi.nlm.nih.gov/pubmed/29551306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2018.03.002
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