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MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport

Neuronal cell morphogenesis depends on proper regulation of microtubule-based transport, but the underlying mechanisms are not well understood. Here, we report our study of MAP7, a unique microtubule-associated protein that interacts with both microtubules and the motor protein kinesin-1. Structure-...

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Publicat a:eLife
Autors principals: Tymanskyj, Stephen R, Yang, Benjamin H, Verhey, Kristen J, Ma, Le
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133550/
https://ncbi.nlm.nih.gov/pubmed/30132755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36374
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