Chronic restraint stress disturbs meiotic resumption through APC/C-mediated cyclin B1 excessive degradation in mouse oocytes

Psychological stress, which exerts detrimental effects on human reproduction, may compromise the meiotic competence of oocytes. Meiotic resumption, germinal vesicle breakdown (GVBD), is the first milestone to confer meiotic competence to oocytes. In the practice of assisted reproductive technology (...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Sun, Junyan, Guo, Ying, Zhang, Qiuwan, Bu, Shixia, Li, Boning, Wang, Qian, Lai, Dongmei
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133342/
https://ncbi.nlm.nih.gov/pubmed/29911914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1471316
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