Naturally produced type I IFNs enhance human myeloid dendritic cell maturation and IL-12p70 production and mediate elevated effector functions in innate and adaptive immune cells

There has recently been a paradigm shift in the field of dendritic cell (DC)-based immunotherapy, where several clinical studies have confirmed the feasibility and advantageousness of using directly isolated human blood-derived DCs over in vitro differentiated subsets. There are two major DC subsets...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Sköld, Annette E., Mathan, Till S. M., van Beek, Jasper J. P., Flórez-Grau, Georgina, van den Beukel, Michelle D., Sittig, Simone P., Wimmers, Florian, Bakdash, Ghaith, Schreibelt, Gerty, de Vries, I. Jolanda M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132867/
https://ncbi.nlm.nih.gov/pubmed/30019146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-018-2204-2
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