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Are laboratory parameter (biomarker) values similar to the healthy volunteer reference range in all patient populations?
BACKGROUND: Liver biomarkers alanine aminotransferase (ALT) and bilirubin in patients with hepatitis are above the healthy volunteer reference range (HVRR) at baseline (prior to receiving the clinical trial medication). Discussions continue as how to best distinguish drug-induced liver injury in pat...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6132491/ https://ncbi.nlm.nih.gov/pubmed/30233139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S173671 |
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