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Astragaloside IV/lncRNA-TUG1/TRAF5 signaling pathway participates in podocyte apoptosis of diabetic nephropathy rats

OBJECTIVE: This study aims to figure out the mechanism of astragaloside IV (AS-IV) in the protection of podocyte apoptosis in diabetic nephropathy (DN) rats. MATERIALS AND METHODS: Streptozotocin (STZ) was used to induce diabetes in rats, and the diabetic rats were treated with 5 mg/kg/d of AS-IV fo...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Lei, Xiao, Zhang, Limei, Li, Zonglin, Ren, Jigang
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132489/
https://ncbi.nlm.nih.gov/pubmed/30233141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S166525
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