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Loss of TrkB Signaling in Parvalbumin-Expressing Basket Cells Results in Network Activity Disruption and Abnormal Behavior

The GABAergic system is regulated by the brain-derived neurotrophic factor (BDNF)/Tropomyosin-related kinase B (TrkB) pathway, but the cell-intrinsic role of TrkB signaling in parvalbumin cortical interneuron development and function is unclear. We performed conditional ablation of the TrkB receptor...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Main Authors: Xenos, Dionysios, Kamceva, Marija, Tomasi, Simone, Cardin, Jessica A, Schwartz, Michael L, Vaccarino, Flora M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132287/
https://ncbi.nlm.nih.gov/pubmed/28968898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhx173
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