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Synthesis of 5-Methylene-2-pyrrolones
A facile, one-pot synthetic method for the synthesis of 5-methylene-2-pyrrolones (5MPs) from inexpensive furfuryl acetate is described. Bromine oxidation and trapping of the in situ generated 1,4-dicarbonyl compound by a primary amine provided the corresponding 5MPs in 50–69% yield.
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| Publicado no: | Org Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6132240/ https://ncbi.nlm.nih.gov/pubmed/30063360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b02030 |
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