Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control

BACKGROUND: Despite the low level of viral replication in HIV controllers (HICs), studies have reported viral mutations related to escape from cytotoxic T-lymphocyte (CTL) response in HIV-1 plasma sequences. Thus, evaluating the dynamics of the emergence of CTL-escape mutants in HICs reservoirs is i...

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Bibliographic Details
Published in:Retrovirology
Main Authors: Caetano, Diogo Gama, Côrtes, Fernanda Heloise, Bello, Gonzalo, Teixeira, Sylvia Lopes Maia, Hoagland, Brenda, Grinsztejn, Beatriz, Veloso, Valdilea Gonçalves, Guimarães, Monick Lindenmeyer, Morgado, Mariza Gonçalves
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131818/
https://ncbi.nlm.nih.gov/pubmed/30201008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-018-0444-z
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