Pluronic-based nano-self-assemblies of bacitracin A with a new mechanism of action for an efficient in vivo therapeutic effect against bacterial peritonitis

BACKGROUND: Although assemblies of hydrophobic-modified bacitracin A with PLGA (Nano-BA(PLGA)) have demonstrated promising antibacterial activities against both Gram-positive and Gram-negative bacteria, the desirable antibacterial potency has remained challenging due to the low solubility of Nano-BA...

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Bibliografiske detaljer
Udgivet i:J Nanobiotechnology
Main Authors: Hong, Wei, Liu, Lipeng, Zhao, Yining, Liu, Yinghui, Zhang, Dexian, Liu, Mingchun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131780/
https://ncbi.nlm.nih.gov/pubmed/30205822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0397-3
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