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Trastuzumab-mediated cardiotoxicity: current understanding, challenges, and frontiers

Trastuzumab, an epidermal growth factor receptor 2 (HER2) targeting humanized monoclonal antibody, has been approved for the treatment HER2-positive breast cancer and HER2-positve metastatic gastric cancer. However, cardiotoxicity associated with its clinical application poses challenges for clinici...

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Détails bibliographiques
Publié dans:Antib Ther
Auteurs principaux: Mohan, Nishant, Jiang, Jiangsong, Dokmanovic, Milos, Wu, Wen Jin
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131716/
https://ncbi.nlm.nih.gov/pubmed/30215054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tby003
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