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A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research

The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti-emetic properties and repurposing from one indication to another is a continuing trend. Notably, the discoveries have occurred against a background of company mergers an...

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Publicat a:Front Pharmacol
Autors principals: Sanger, Gareth J., Andrews, Paul L. R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131675/
https://ncbi.nlm.nih.gov/pubmed/30233361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00913
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