Studying Huntington’s Disease in Yeast: From Mechanisms to Pharmacological Approaches

Huntington’s disease (HD) is a neurodegenerative disorder that leads to progressive neuronal loss, provoking impaired motor control, cognitive decline, and dementia. So far, HD remains incurable, and available drugs are effective only for symptomatic management. HD is caused by a mutant form of the...

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Dettagli Bibliografici
Pubblicato in:Front Mol Neurosci
Autori principali: Hofer, Sebastian, Kainz, Katharina, Zimmermann, Andreas, Bauer, Maria A., Pendl, Tobias, Poglitsch, Michael, Madeo, Frank, Carmona-Gutierrez, Didac
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131589/
https://ncbi.nlm.nih.gov/pubmed/30233317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00318
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