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Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS
Altered cellular biomechanics have been implicated as key photogenic triggers in age-related diseases. An aberrant liquid-to-solid phase transition, observed in in vitro reconstituted droplets of FUS protein, has been recently proposed as a possible pathogenic mechanism for amyotrophic lateral scler...
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| Publié dans: | Commun Biol |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6131551/ https://ncbi.nlm.nih.gov/pubmed/30272018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0148-x |
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