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Inhibition of microRNA-299-5p sensitizes glioblastoma cells to temozolomide via the MAPK/ERK signaling pathway

Glioblastomas (GBMs) are a lethal class of brain cancer, with a median survival <15 months in spite of therapeutic advances. The poor prognosis of GBM is largely attributed to acquired chemotherapy resistance, and new strategies are urgently needed to target resistant glioma cells. Here we report...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Peng, Yujiang, He, Xijun, Chen, Huihui, Duan, Hongyu, Shao, Bo, Yang, Fan, Li, Huiyong, Yang, Pengxiang, Zeng, Yu, Zheng, Jinrong, Li, Yongsheng, Hu, Jiachang, Lin, Liguo, Teng, Lingfang
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131327/
https://ncbi.nlm.nih.gov/pubmed/30061180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181051
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