Increased inflammation and brain glutamate define a subtype of depression with decreased regional homogeneity, impaired network integrity, and anhedonia

Combined increases in peripheral inflammation and brain glutamate may identify a subtype of depression with distinct neuroimaging signatures. Two contrasting subgroups of depressed subjects—with and without combined elevations in plasma C-reactive protein (CRP) and basal ganglia glutamate (high and...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Haroon, Ebrahim, Chen, Xiangchuan, Li, Zhihao, Patel, Thrusharth, Woolwine, Bobbi J., Hu, Xiaoping P., Felger, Jennifer C., Miller, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131242/
https://ncbi.nlm.nih.gov/pubmed/30202011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0241-4
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