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Distribution of Antisense Oligonucleotides in Rat Eyeballs Using MALDI Imaging Mass Spectrometry
Oligonucleotide-based therapeutics such as antisense oligonucleotides, small interfering RNAs (siRNAs), decoy and aptamer have been extensively developed. To investigate the pharmacokinetics of oligonucleotide therapeutics, it is common to label a radioisotope in a nucleic acid and visualize it. How...
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| Veröffentlicht in: | Mass Spectrom (Tokyo) |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Mass Spectrometry Society of Japan
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6131115/ https://ncbi.nlm.nih.gov/pubmed/30214850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5702/massspectrometry.A0070 |
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