Cerebrospinal Fluid Tau, Aβ, and sTREM2 in Former National Football League Players: Modeling the Relationship between Repetitive Head Impacts, Microglial Activation, and Neurodegeneration

INTRODUCTION: Cerebrospinal fluid (CSF) protein analysis may facilitate detection and elucidate mechanisms of neurological consequences from repetitive head impacts (RHI), such as chronic traumatic encephalopathy (CTE). We examined CSF concentrations of total tau (t-tau), phosphorylated tau (p-tau),...

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Vydáno v:Alzheimers Dement
Hlavní autoři: Alosco, Michael L., Tripodis, Yorghos, Fritts, Nathan G., Heslegrave, Amanda, Baugh, Christine M., Conneely, Shannon, Mariani, Megan, Martin, Brett M., Frank, Samuel, Mez, Jesse, Stein, Thor D., Cantu, Robert C., McKee, Ann C., Shaw, Leslie M., Trojanowski, John Q., Blennow, Kaj, Zetterberg, Henrik, Stern, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131058/
https://ncbi.nlm.nih.gov/pubmed/30049650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.05.004
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