Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition

Fucosylated glycosaminoglycan (FG), a structurally complex glycosaminoglycan found up to now exclusively in sea cucumbers, has distinct anticoagulant properties, notably a strong inhibitory activity of intrinsic factor Xase complex (FXase). Knowledge of the FG structures could facilitate the develop...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Yin, Ronghua, Zhou, Lutan, Gao, Na, Li, Zi, Zhao, Longyan, Shang, Feineng, Wu, Mingyi, Zhao, Jinhua
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130965/
https://ncbi.nlm.nih.gov/pubmed/30030375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003809
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