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Behavioural phenotyping, learning and memory in young and aged growth hormone-releasing hormone-knockout mice

BACKGROUND: Growth hormone-releasing hormone (GHRH) plays an important role in brain functions. The aim of this study was to examine cognitive functions and emotional behaviour in a mouse model of isolated GH deficiency due to bi-allelic ablation of the GHRH gene (GHRH knockout, GHRHKO). METHODS: Le...

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Publicat a:Endocr Connect
Autors principals: Leone, Sheila, Recinella, Lucia, Chiavaroli, Annalisa, Ferrante, Claudio, Orlando, Giustino, Vacca, Michele, Salvatori, Roberto, Brunetti, Luigi
Format: Artigo
Idioma:Inglês
Publicat: Bioscientifica Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130317/
https://ncbi.nlm.nih.gov/pubmed/30300535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-18-0165
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