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Systemic Candidiasis and TLR2 Agonist Exposure Impact the Antifungal Response of Hematopoietic Stem and Progenitor Cells

We have previously demonstrated that Candida albicans induces differentiation of hematopoietic stem and progenitor cells (HSPCs) toward the myeloid lineage both in vitro and in vivo in a TLR2- and Dectin-1-dependent manner, giving rise to functional macrophages. In this work, we used an ex vivo mode...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Martínez, Alba, Bono, Cristina, Megías, Javier, Yáñez, Alberto, Gozalbo, Daniel, Gil, M. Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130230/
https://ncbi.nlm.nih.gov/pubmed/30234030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00309
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