A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA

Genomes are promiscuously transcribed, necessitating mechanisms that facilitate the sorting of RNA for function or destruction. The polyA (pA) tail is one such distinguishing feature, which in the Saccharomyces cerevisiae nucleus is bound by the Nab2p protein, yielding transcript protection. As Nab2...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Tudek, Agnieszka, Schmid, Manfred, Makaras, Marius, Barrass, J. David, Beggs, Jean D., Jensen, Torben Heick
Format: Artigo
Language:Inglês
Published: Cell Press 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130047/
https://ncbi.nlm.nih.gov/pubmed/30157437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.103
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