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The Search for Genetic Polymorphisms in the Homocysteine/Folate Pathway That Contribute to the Etiology of Human Neural Tube Defects

In this paper, we trace the history of current research into the genetic and biochemical mechanisms that underlie folate-preventable neural tube defects (NTDs). The inspired suggestion by Smithells that common vitamins might prevent NTDs ignited a decade of biochemical investigations—first exploring...

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Detalhes bibliográficos
Publicado no:Birth Defects Res A Clin Mol Teratol
Main Authors: Molloy, Anne M., Brody, Lawrence C., Mills, James L., Scott, John M., Kirke, Peadar N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129971/
https://ncbi.nlm.nih.gov/pubmed/19235830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20566
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