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Pharmacologic characterization of CT-711, a novel dual inhibitor of ALK and c-Met
Anaplastic lymphoma kinase (ALK) is a validated molecular target for patients harboring ALK rearrangement, which triggers the development of ALK inhibitors. However, the activation of mesenchymal-epithelial transition factor (c-Met) has emerged as a common cause of acquired resistance induced by sel...
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| 發表在: | Am J Cancer Res |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
e-Century Publishing Corporation
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6129499/ https://ncbi.nlm.nih.gov/pubmed/30210922 |
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