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Pharmacologic characterization of CT-711, a novel dual inhibitor of ALK and c-Met

Anaplastic lymphoma kinase (ALK) is a validated molecular target for patients harboring ALK rearrangement, which triggers the development of ALK inhibitors. However, the activation of mesenchymal-epithelial transition factor (c-Met) has emerged as a common cause of acquired resistance induced by sel...

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Bibliografske podrobnosti
izdano v:Am J Cancer Res
Main Authors: Wang, Lei, Gao, Mingzhao, Tong, Mengya, Xie, Chengying, He, Ye, Fu, Li, Li, Yun, Fu, Haoyu, Lou, Liguang
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129499/
https://ncbi.nlm.nih.gov/pubmed/30210922
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