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Tocilizumab for the Treatment of Mevalonate Kinase Deficiency

Mevalonate kinase deficiency (MKD) is a severe autoinflammatory disease caused by recessive mutations in MVK resulting in reduced function of the enzyme mevalonate kinase, involved in the cholesterol/isoprenoid pathway. MKD presents with periodic episodes of severe systemic inflammation, poor qualit...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Case Rep Pediatr
Prif Awduron: Rafiq, Nadia K., Lachmann, Helen, Joensen, Frodi, Herlin, Troels, Brogan, Paul A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129367/
https://ncbi.nlm.nih.gov/pubmed/30225156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3514645
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