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Cyproheptadine Regulates Pyramidal Neuron Excitability in Mouse Medial Prefrontal Cortex
Cyproheptadine (CPH), a first-generation antihistamine, enhances the delayed rectifier outward K(+) current (I(K)) in mouse cortical neurons through a sigma-1 receptor-mediated protein kinase A pathway. In this study, we aimed to determine the effects of CPH on neuronal excitability in current-clamp...
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| Publicado no: | Neurosci Bull |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Singapore
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6129243/ https://ncbi.nlm.nih.gov/pubmed/29671217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-018-0225-7 |
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