Varicella Zoster Virus Induces Nuclear Translocation of the Neurokinin-1 Receptor, Promoting Lamellipodia Formation and Viral Spread in Spinal Astrocytes

BACKGROUND: Varicella zoster virus (VZV) can present as a myelopathy with spinal astrocyte infection. Recent studies support a role for the neurokinin-1 receptor (NK-1R) in virus infections, as well as for cytoskeletal alterations that may promote viral spread. Thus, we examined the role of NK-1R in...

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Detalles Bibliográficos
Publicado en:J Infect Dis
Main Authors: Bubak, Andrew N, Como, Christina N, Blackmon, Anna M, Frietze, Seth, Mescher, Teresa, Jones, Dallas, Cohrs, Randall J, Paucek, Petr, Baird, Nicholas L, Nagel, Maria A
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Major Articles and Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129113/
https://ncbi.nlm.nih.gov/pubmed/29788447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy297
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