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Implications for the impairment of the rapid channel closing of Proteomonas sulcata anion channelrhodopsin 1 at high Cl(−) concentrations

Natural anion channelrhodopsins (ACRs) have recently received increased attention because of their effectiveness in optogenetic manipulation for neuronal silencing. In this study, we focused on Proteomonas sulcata ACR1 (PsuACR1), which has rapid channel closing kinetics and a rapid recovery to the i...

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Vydáno v:Sci Rep
Hlavní autoři: Tsukamoto, Takashi, Kikuchi, Chihiro, Suzuki, Hiromu, Aizawa, Tomoyasu, Kikukawa, Takashi, Demura, Makoto
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128917/
https://ncbi.nlm.nih.gov/pubmed/30194401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31742-6
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