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Recipient single nucleotide polymorphisms in Paneth cell antimicrobial peptide genes and acute graft-versus-host disease: Analysis of BMT CTN-0201 and -0901 samples

Host genetics shape the gut microbiota, and gut dysbiosis increases the risk of acute graft-versus-host disease (aGVHD). Paneth cells and microbiota have interactions that contribute to immune regulation. α-defensin-5 (HD5) and regenerating islet-derived protein 3 alpha (Reg3A) are the most abundant...

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Dettagli Bibliografici
Pubblicato in:Br J Haematol
Autori principali: Rashidi, Armin, Shanley, Ryan, Yohe, Sophia L., Thyagarajan, Bharat, Curtsinger, Julie, Anasetti, Claudio, Waller, Edmund K., Scott, Bart L., Blazar, Bruce R., Weisdorf, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128755/
https://ncbi.nlm.nih.gov/pubmed/30004111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.15492
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