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Mean platelet volume and lymphocyte-to-monocyte ratio are associated with shorter progression-free survival in EGFR-mutant lung adenocarcinoma treated by EGFR tyrosine kinase inhibitor

BACKGROUND: A growing body of evidence supports the role of platelets in cancer metastasis, escape from immune surveillance, and angiogenesis. Mean platelet volume (MPV), which reflects platelet turnover, is reported routinely as part of automated complete blood count. Accumulating evidence suggests...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Watanabe, Kousuke, Yasumoto, Atsushi, Amano, Yosuke, Kage, Hidenori, Goto, Yasushi, Yatomi, Yutaka, Takai, Daiya, Nagase, Takahide
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128600/
https://ncbi.nlm.nih.gov/pubmed/30192878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203625
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