Sirolimus Gel Treatment vs Placebo for Facial Angiofibromas in Patients With Tuberous Sclerosis Complex: A Randomized Clinical Trial

IMPORTANCE: Most patients with tuberous sclerosis complex (TSC), an autosomal-dominant disorder that is caused by the constitutive activation of mammalian target of rapamycin, experience disfigurement caused by skin lesions involving facial angiofibromas. Many have been left untreated because of a l...

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Detalhes bibliográficos
Publicado no:JAMA Dermatol
Main Authors: Wataya-Kaneda, Mari, Ohno, Yuuki, Fujita, Yasuyuki, Yokozeki, Hiroo, Niizeki, Hironori, Ogai, Masaaki, Fukai, Kazuyoshi, Nagai, Hiroshi, Yoshida, Yuichi, Hamada, Izumi, Hio, Taihei, Shimizu, Kenji, Murota, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128500/
https://ncbi.nlm.nih.gov/pubmed/29800026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamadermatol.2018.1408
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