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Ratiometric Raman imaging reveals the new anti-cancer potential of lipid targeting drugs

De novo lipid synthesis is upregulated in cancer cells and inhibiting these pathways has displayed anti-tumour activity. Here we use Raman spectroscopy, focusing solely on high wavenumber spectra, to detect changes in lipid composition in single cells in response to drugs targeting de novo lipid syn...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Jamieson, Lauren E., Wetherill, Corinna, Faulds, Karen, Graham, Duncan
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128370/
https://ncbi.nlm.nih.gov/pubmed/30258563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02312c
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